Evidence for the Presence of Two Novel Pestivirus Species

The genus Pestivirus of the family Flaviviridae comprises four species, namely Bovine viral diarrhea virus-1 (BVDV-1), BVDV-2, Border disease virus (BDV), and Classical swine fever virus (CSFV). Comparative analyses of partial sequences have suggested that pestivirus isolates from giraffe (Giraffe-1) and reindeer (Reindeer-1) are distinct from the established species (Becher et al., Virology 262, 64–71, 1999). In this study, we report the complete genomic sequences of pestivirus […]

Species characterization in the genus pestivirus according to palindromic nucleotide substitutions in the 5′ untranslated region

The palindromic nucleotide substitutions (PNS) at the three variable loci (V1, V2, and V3) in the 5′ untranslated region (UTR) of the Pestivirus genome have been considered for taxonomical segregation of the species, through the evaluation of 533 strains. On the basis of qualitative and quantitative secondary structure characteristics, species have been identified within the […]